Lyophilized Peptides
TB-500 (Thymosin Beta-4)
Literature identity: thymosin β4 residues 17–23; Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH
A seven-residue acetylated peptide corresponding to residues 17–23 of thymosin β4; it is not the full-length thymosin β4 peptide.
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Lot documentation
Current Certificate of Analysis
11 approved certificates are attached to this product record.
View all historical COAs (8)
Technical information
Chemical & material record
Presented in a scientific-catalog format so the material can be evaluated by identity, form and documentation before purchase.
- Identity
- TB-500 research peptide; salt form controlled by the approved specification
- Synonyms
- Literature identity: thymosin β4 residues 17–23; Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH
- CAS number
- See approved Remetide material specification
- Molecular formula
- See approved Remetide material specification
- Formula weight
- See approved Remetide material specification
- Sequence / identity note
- Literature identity: Ac-LKKTETQ-OH; production identity must match the approved lot record
- Manufacturer
- Remetide
- Manufacturing role
- Custom peptide synthesis and manufacture
- Form
- Lyophilized, non-sterile research material
- Purity specification
- Target ≥99% by RP-HPLC; lot result controls
- Storage
- -20°C, dry and protected from light; follow lot documentation
- Pack size
- Research pack · supplied amount shown on product record
- Catalog number
- TB-PW
Research context
Published research & product context
Published literature is presented separately from lot-specific identity, purity and analytical results.
TB-500 is an acetylated heptapeptide corresponding to amino-acid residues 17–23 of thymosin β4, an actin-sequestering peptide. Distinguishing this fragment from full-length thymosin β4 is essential for identity, formula, mass and literature interpretation.
Published research reported inhibition of PDGF-BB-stimulated hepatic stellate-cell proliferation and migration at 10 ng/mL. A separate mouse study evaluated topical TB-500 in a skin-wound model. These are experimental observations and are not administration guidance.
Selected published findings
- Corresponds to the actin-binding-domain region of thymosin β4.
- Inhibited PDGF-BB-stimulated hepatic stellate-cell proliferation and migration in a published cellular study.
- Was evaluated in a non-clinical mouse skin-wound model.
References and product citations 2
- Shah, R., Reyes-Gordillo, K., and Rojkind, M. Thymosin β4 inhibits PDGF-BB-induced activation, proliferation, and migration of human hepatic stellate cells via its actin-binding domain. Expert Opinion on Biological Therapy 18(sup1), 177–184 (2018).
- Huang, C.M., Wang, C.C., Barnes, S., et al. In vivo detection of secreted proteins from wounded skin using capillary ultrafiltration probes and mass-spectrometric proteomics. Proteomics 6(21), 5805–5814 (2006).
Literature interpretation: This summary describes published experimental literature and is not a lot specification, clinical claim, use instruction or representation that the supplied research material will reproduce a published result. This record intentionally excludes dosing, administration, clinical outcomes, patient eligibility and therapeutic comparisons.
Intended laboratory context
Illustrative applications
- Analytical comparison
- Method development
- In-vitro laboratory investigation
- Protocol development
Documentation package
Documentation
- PDFCertificate of AnalysisSample
- PDFHPLC chromatogramSample
- PDFMass-spectrometry summarySample
- PDFHandling statementSample
For laboratory research workflows only. Not for administration to humans or animals and not supplied with dosing or reconstitution guidance.
Research procurement FAQ
Plain answers about research-use boundaries, documentation, accounts, and ordering. Not medical or clinical guidance.
What is this product record for?
TB-500 (Thymosin Beta-4) is presented as a research catalog record with identity, format, pack options, specification language, and lot-documentation pathways for qualified laboratory procurement. It is not a consumer or clinical product.
How do I order this item?
Open the product record, choose the pack option, and check out as a guest (no account needed) or signed in. If the item is quotation-only (bulk API or custom project), use the quotation pathway instead of standard cart checkout.
What does “research use only” mean?
Research use only (RUO) means these materials are intended for legitimate non-clinical laboratory investigation. They are not offered for human or animal administration, compounding, diagnosis, treatment, prevention, or consumer use.
Do I need an account to browse or buy?
No. Guest checkout is open: you can browse the catalog and order without creating an account. Subscribe & Save orders get an account created automatically so you can manage or cancel the subscription. Lot documentation stays tied to every order either way.
What documentation accompanies a research material?
Lot-level documentation may include a Certificate of Analysis (COA), identity/purity method context, and related analytical records. Always defer to the approved lot record and material specification for the specific shipment.
How is purity described?
Purity statements identify the analytical method (for example RP-HPLC) and defer to the released lot result and any molecule-specific specification. Public copy never replaces the lot COA.
How does shipping work for research materials?
Shipping follows the carrier and packaging appropriate for the material specification. Inspect shipments promptly and contact support with the order number, catalog number, and lot if anything looks incorrect. Unauthorized returns of research materials are not accepted.
Does Simple Life Science provide dosing or medical guidance?
No. We do not provide dosing, administration, medical advice, patient selection, or clinical-use instructions. Website content and technical support stay within laboratory research context.
Need a current record?
Documentation before decision-making.
Reference TB-PW and the applicable lot when contacting technical support. Published files support evaluation but do not replace the approved lot COA or material specification.
View documentation model