Lyophilized Peptides
GHK-CU 100MG
Gly-His-Lys-Cu(II)
A copper(II) complex of the Gly-His-Lys tripeptide used in biochemical, cell-culture and analytical research.
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Lot documentation
Current Certificate of Analysis
16 approved certificates are attached to this product record.
View all historical COAs (13)
Technical information
Chemical & material record
Presented in a scientific-catalog format so the material can be evaluated by identity, form and documentation before purchase.
- Identity
- GHK-Cu acetate
- Synonyms
- Gly-His-Lys-Cu(II)
- CAS number
- 300801-03-0
- Molecular formula
- C14H22CuN6O4 · C2H4O2
- Formula weight
- 462.0 Da
- Sequence / identity note
- Gly-His-Lys copper complex
- Manufacturer
- Remetide
- Manufacturing role
- Custom peptide synthesis and manufacture
- Form
- Lyophilized, non-sterile research material
- Purity specification
- Target ≥99% by RP-HPLC; lot result controls
- Storage
- -20°C, dry and protected from light; follow lot documentation
- Pack size
- 100 mg
- Catalog number
- GHKC-PW-100MG
Research context
Published research & product context
Published literature is presented separately from lot-specific identity, purity and analytical results.
GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine. Published cell-culture research has examined its effects on extracellular-matrix markers, fibroblast proliferation and inflammatory signaling.
Reported studies found increased proliferation, collagen and secreted pro-MMP-2 in isolated human fibroblasts at 1 nM. In RAW 264.7 macrophage-like cells, 10 µM GHK-Cu reduced lipopolysaccharide-associated increases in reactive oxygen species, IL-6 and TNF-α. Results remain model and assay dependent.
Selected published findings
- Examined for collagen, glycosaminoglycan, decorin and matrix-remodeling endpoints.
- Examined for oxidative-stress and inflammatory-marker responses in cell models.
- Used as a copper-complexed tripeptide reference in analytical and formulation research.
References and product citations 3
- Siméon, A., Monier, F., Emonard, H., et al. Expression and activation of matrix metalloproteinases in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. Journal of Investigative Dermatology 115(6), 962–968 (2000).
- Maquart, F.X., Pickart, L., Laurent, M., et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Letters 238(2), 343–346 (1988).
- Park, J.R., Lee, H., Kim, S.I., et al. The tripeptide GHK-Cu attenuates lipopolysaccharide-induced inflammatory processes in RAW 264.7 cells. Oncotarget 7(19), 26745–26756 (2016).
Literature interpretation: This summary describes published experimental literature and is not a lot specification, clinical claim, use instruction or representation that the supplied research material will reproduce a published result. This record intentionally excludes dosing, administration, clinical outcomes, patient eligibility and therapeutic comparisons.
Intended laboratory context
Illustrative applications
- Analytical reference use
- Method development
- Comparative chromatography
- Laboratory formulation research
Documentation package
Documentation
- PDFCertificate of AnalysisSample
- PDFAnalytical method noteSample
- PDFHandling statementSample
- PDFLot traceability recordSample
Identity, method and release language remain subject to the approved specification and lot-specific Quality record.
Research procurement FAQ
Plain answers about research-use boundaries, documentation, accounts, and ordering. Not medical or clinical guidance.
What is this product record for?
GHK-CU 100MG is presented as a research catalog record with identity, format, pack options, specification language, and lot-documentation pathways for qualified laboratory procurement. It is not a consumer or clinical product.
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What does “research use only” mean?
Research use only (RUO) means these materials are intended for legitimate non-clinical laboratory investigation. They are not offered for human or animal administration, compounding, diagnosis, treatment, prevention, or consumer use.
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What documentation accompanies a research material?
Lot-level documentation may include a Certificate of Analysis (COA), identity/purity method context, and related analytical records. Always defer to the approved lot record and material specification for the specific shipment.
How is purity described?
Purity statements identify the analytical method (for example RP-HPLC) and defer to the released lot result and any molecule-specific specification. Public copy never replaces the lot COA.
How does shipping work for research materials?
Shipping follows the carrier and packaging appropriate for the material specification. Inspect shipments promptly and contact support with the order number, catalog number, and lot if anything looks incorrect. Unauthorized returns of research materials are not accepted.
Does Simple Life Science provide dosing or medical guidance?
No. We do not provide dosing, administration, medical advice, patient selection, or clinical-use instructions. Website content and technical support stay within laboratory research context.
Need a current record?
Documentation before decision-making.
Reference GHKC-PW-100MG and the applicable lot when contacting technical support. Published files support evaluation but do not replace the approved lot COA or material specification.
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