Intended laboratory context
Illustrative applications
- Analytical reference use
- Method development
- Comparative chromatography
- Laboratory formulation research
Lyophilized Peptides
GHK-CU 100MG
Gly-His-Lys-Cu(II)
A copper(II) complex of the Gly-His-Lys tripeptide used in biochemical, cell-culture and analytical research.
CatalogGHKC-PW-100MG
ManufacturerRemetide
PurityProposed ≥99% by RP-HPLC; lot result controls
Pack100 mg
$55.00 Current catalog price; lot availability controls fulfillment.
AvailabilityIn stock
12199 in stock
For laboratory research use only. Not for human or veterinary use.
GHK-CU 100MG$55.00
01Lot documentationCOA and analytical-record model
02Defined specificationMethod and result remain lot specific
03Tracked fulfillmentShipping method and lot allocation confirmed at order review
04Responsible useNon-clinical laboratory context
Technical information
Chemical & material record
Presented in a scientific-catalog format so the material can be evaluated by identity, form and documentation before purchase.
- Identity
- GHK-Cu acetate
- Synonyms
- Gly-His-Lys-Cu(II)
- CAS number
- 300801-03-0
- Molecular formula
- C14H22CuN6O4 · C2H4O2
- Formula weight
- 462.0 Da
- Sequence / identity note
- Gly-His-Lys copper complex
- Manufacturer
- Remetide
- Manufacturing role
- Custom peptide synthesis and manufacture
- Form
- Lyophilized, non-sterile research material
- Purity specification
- Proposed ≥99% by RP-HPLC; lot result controls
- Storage
- -20°C, dry and protected from light; follow lot documentation
- Pack size
- 100 mg
- Catalog number
- GHKC-PW-100MG
Product description
Published context, clearly separated from lot claims.
A technical catalog should make the chemical record, relevant experimental literature and product-specific documentation independently reviewable.
GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine. Published cell-culture research has examined its effects on extracellular-matrix markers, fibroblast proliferation and inflammatory signaling.
Reported studies found increased proliferation, collagen and secreted pro-MMP-2 in isolated human fibroblasts at 1 nM. In RAW 264.7 macrophage-like cells, 10 µM GHK-Cu reduced lipopolysaccharide-associated increases in reactive oxygen species, IL-6 and TNF-α. Results remain model and assay dependent.
Selected published findings
- Examined for collagen, glycosaminoglycan, decorin and matrix-remodeling endpoints.
- Examined for oxidative-stress and inflammatory-marker responses in cell models.
- Used as a copper-complexed tripeptide reference in analytical and formulation research.
References and product citations 3
- Siméon, A., Monier, F., Emonard, H., et al. Expression and activation of matrix metalloproteinases in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. Journal of Investigative Dermatology 115(6), 962–968 (2000).
- Maquart, F.X., Pickart, L., Laurent, M., et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Letters 238(2), 343–346 (1988).
- Park, J.R., Lee, H., Kim, S.I., et al. The tripeptide GHK-Cu attenuates lipopolysaccharide-induced inflammatory processes in RAW 264.7 cells. Oncotarget 7(19), 26745–26756 (2016).
Literature interpretation: This summary describes published experimental literature and is not a lot specification, clinical claim, use instruction or representation that the supplied research material will reproduce a published result. This record intentionally excludes dosing, administration, clinical outcomes, patient eligibility and therapeutic comparisons.
Proposed package
Documentation
- PDFCertificate of AnalysisSample
- PDFAnalytical method noteSample
- PDFHandling statementSample
- PDFLot traceability recordSample
Identity, method and release language remain subject to the approved specification and lot-specific Quality record.
Need a current record?
Documentation before decision-making.
Reference GHKC-PW-100MG and the applicable lot when contacting technical support. Published files support evaluation but do not replace the approved lot COA or material specification.
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