For laboratory research use onlyNot for human or animal consumption

Lyophilized Peptides

Tirzepatide Research Reference — 10 mg

LY3298176

A synthetic, lipidated peptide research reference characterized in published studies as a dual agonist of human GLP-1R and GIPR.

CatalogGT-PW-10MG
ManufacturerRemetide
PurityTarget ≥99% by RP-HPLC; lot result controls
Pack10 mg
$93.00 Current catalog price; lot availability controls fulfillment.
AvailabilityIn stock

12604 in stock

For laboratory research use only. Not for human or veterinary use.

01Lot documentationCOA and analytical-record model
02Defined specificationMethod and result remain lot specific
03Tracked fulfillmentShipping method and lot allocation confirmed at order review
04Responsible useNon-clinical laboratory context

Lot documentation

Current Certificate of Analysis

25 approved certificates are attached to this product record.

Reported 2026-05-23Lot GT10-052026-299.88% purity · 13.69 mg
Open COA
Reported 2026-05-23Lot GT10-052026-299.88% purity · 13.69 mg
Open COA
Reported 2026-05-08Lot GT10-052026-299.30% purity · 11.62 mg
Open COA
Reported 2026-05-08Lot GT10-052026-299.30% purity · 11.62 mg
Open COA
Reported 2026-05-08Lot GT10-052026-299.30% purity · 11.62 mg
Open COA
Reported 2026-03-11Lot GT10-032026-199.78% purity · 10.43 mg
Open COA
Reported 2026-03-11Lot GT110-032026-199.78% purity · 10.43 mg
Open COA
Reported 2025-12-18Lot GT10-8064199.856% purity · 9.91 mg
Open COA
Reported 2025-12-12Lot GT10-6041499.856% purity
Open COA
Reported 2025-12-12Lot GT10-6041499.856% purity · 10.29 mg
Open COA
Reported 2025-12-08Lot GT10-1069299.862% purity
Open COA
Reported 2025-12-08Lot GT10-1069299.862% purity · 10.16 mg
Open COA
Reported 2025-11-27Lot GT10-11202025-J99.906% purity
Open COA
Reported 2025-11-27Lot GI16-11202025-J99.906% purity · 11.09 mg
Open COA
Reported 2025-10-16Lot GT10-10142025-H99.98% purity · 12.24 mg
Open COA
Reported 2025-10-16Lot GT10-10142025-H99.98% purity · 12.24 mg
Open COA
Reported 2025-10-15Lot T1R1008192025-1099.957% purity · 12.72 mg
Open COA
Reported 2025-10-15Lot TIR1008192025-1099.957% purity · 12.72 mg
Open COA
Reported 2025-08-20Lot T1R 1008162025-1099.91% purity · 11.58 mg
Open COA
Reported 2025-08-20Lot TIR 1008162025-1099.91% purity · 11.58 mg
Open COA
Reported 2025-08-13Lot GT10-08112025-J99.76% purity
Open COA
Reported 2025-08-13Lot GT10-08112025-J99.76% purity · 9.77 mg
Open COA
Reported 2025-07-27Lot TIR 1007232025-0999.89% purity · 11.21 mg
Open COA
Reported 2025-07-27Lot TIR 1007232025-0999.89% purity · 11.21 mg
Open COA
Reported 2025-06-27Lot TIRZ1006202-N99.92% purity · 12.20 mg
Open COA

Technical information

Chemical & material record

Presented in a scientific-catalog format so the material can be evaluated by identity, form and documentation before purchase.

Identity
Tirzepatide research reference
Synonyms
LY3298176
CAS number
2023788-19-2
Molecular formula
C225H348N48O68
Formula weight
4,813.5 Da
Sequence / identity note
39-residue modified peptide; sequence controlled in the technical record
Manufacturer
Remetide
Manufacturing role
Custom peptide synthesis and manufacture
Form
Lyophilized, non-sterile research material
Purity specification
Target ≥99% by RP-HPLC; lot result controls
Storage
-20°C, dry and protected from light; follow lot documentation
Pack size
10 mg
Catalog number
GT-PW-10MG

Research context

Published research & product context

Published literature is presented separately from lot-specific identity, purity and analytical results.

Tirzepatide (LY3298176) is a 39-residue modified peptide studied as an agonist of glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR). Published work has characterized receptor signaling, receptor internalization and downstream metabolic endpoints in non-clinical models.

In human receptor-expressing HEK293 systems, reported cAMP EC50 values were 6.54 nM at GLP-1R and 1.01 nM at GIPR; receptor internalization was also evaluated at 100 nM. These literature values are assay specific and are not release criteria for the supplied material.

Selected published findings

  • Induced cAMP signaling in HEK293 cells expressing human GLP-1R or GIPR.
  • Induced internalization of GLP-1R and GIPR in receptor-expressing cellular systems.
  • Was evaluated in mouse models for metabolic and airway-response endpoints.
References and product citations 3
  1. Willard, F.S., Douros, J.D., Gabe, M.B.N., et al. Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist. JCI Insight 5(17), e140532 (2020).
  2. Samms, R.J., Coghlan, M.P., and Sloop, K.W. How may GIP enhance the therapeutic efficacy of GLP-1? Trends in Endocrinology & Metabolism 31(6), 410–421 (2020).
  3. Toki, S., Goleniewska, K., Zhang, J., et al. GIP receptor agonism suppresses allergic airway inflammation in obese mice. Journal of Allergy and Clinical Immunology (2023).

Literature interpretation: This summary describes published experimental literature and is not a lot specification, clinical claim, use instruction or representation that the supplied research material will reproduce a published result. This record intentionally excludes dosing, administration, clinical outcomes, patient eligibility and therapeutic comparisons.

Intended laboratory context

Illustrative applications

  • Analytical method development
  • Identity comparison
  • Qualified receptor-assay research
  • Controlled non-clinical laboratory investigation

Documentation package

Documentation

  • PDFIllustrative Certificate of AnalysisSample
  • PDFHPLC chromatogramSample
  • PDFMass-spectrometry summarySample
  • PDFMaterial handling statementSample
Responsible-use statement

Not for clinical, diagnostic, compounding, therapeutic, human or veterinary use. Current labeling, specification and lot documentation control.

Need a current record?

Documentation before decision-making.

Reference GT-PW-10MG and the applicable lot when contacting technical support. Published files support evaluation but do not replace the approved lot COA or material specification.

View documentation model