Lyophilized Peptides
TB-500 (Thymosin Beta-4)
Literature identity: thymosin β4 residues 17–23; Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH
A seven-residue acetylated peptide corresponding to residues 17–23 of thymosin β4; it is not the full-length thymosin β4 peptide.
For laboratory research use only. Not for human or veterinary use.
Lot documentation
Current Certificate of Analysis
13 approved certificates are attached to this product record.
Technical information
Chemical & material record
Presented in a scientific-catalog format so the material can be evaluated by identity, form and documentation before purchase.
- Identity
- TB-500 research peptide; salt form controlled by the approved specification
- Synonyms
- Literature identity: thymosin β4 residues 17–23; Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH
- CAS number
- See approved Remetide material specification
- Molecular formula
- See approved Remetide material specification
- Formula weight
- See approved Remetide material specification
- Sequence / identity note
- Literature identity: Ac-LKKTETQ-OH; production identity must match the approved lot record
- Manufacturer
- Remetide
- Manufacturing role
- Custom peptide synthesis and manufacture
- Form
- Lyophilized, non-sterile research material
- Purity specification
- Target ≥99% by RP-HPLC; lot result controls
- Storage
- -20°C, dry and protected from light; follow lot documentation
- Pack size
- Research pack · supplied amount shown on product record
- Catalog number
- TB-PW
Research context
Published research & product context
Published literature is presented separately from lot-specific identity, purity and analytical results.
TB-500 is an acetylated heptapeptide corresponding to amino-acid residues 17–23 of thymosin β4, an actin-sequestering peptide. Distinguishing this fragment from full-length thymosin β4 is essential for identity, formula, mass and literature interpretation.
Published research reported inhibition of PDGF-BB-stimulated hepatic stellate-cell proliferation and migration at 10 ng/mL. A separate mouse study evaluated topical TB-500 in a skin-wound model. These are experimental observations and are not administration guidance.
Selected published findings
- Corresponds to the actin-binding-domain region of thymosin β4.
- Inhibited PDGF-BB-stimulated hepatic stellate-cell proliferation and migration in a published cellular study.
- Was evaluated in a non-clinical mouse skin-wound model.
References and product citations 2
- Shah, R., Reyes-Gordillo, K., and Rojkind, M. Thymosin β4 inhibits PDGF-BB-induced activation, proliferation, and migration of human hepatic stellate cells via its actin-binding domain. Expert Opinion on Biological Therapy 18(sup1), 177–184 (2018).
- Huang, C.M., Wang, C.C., Barnes, S., et al. In vivo detection of secreted proteins from wounded skin using capillary ultrafiltration probes and mass-spectrometric proteomics. Proteomics 6(21), 5805–5814 (2006).
Literature interpretation: This summary describes published experimental literature and is not a lot specification, clinical claim, use instruction or representation that the supplied research material will reproduce a published result. This record intentionally excludes dosing, administration, clinical outcomes, patient eligibility and therapeutic comparisons.
Intended laboratory context
Illustrative applications
- Analytical comparison
- Method development
- In-vitro laboratory investigation
- Protocol development
Documentation package
Documentation
- PDFCertificate of AnalysisSample
- PDFHPLC chromatogramSample
- PDFMass-spectrometry summarySample
- PDFHandling statementSample
For laboratory research workflows only. Not for administration to humans or animals and not supplied with dosing or reconstitution guidance.
Need a current record?
Documentation before decision-making.
Reference TB-PW and the applicable lot when contacting technical support. Published files support evaluation but do not replace the approved lot COA or material specification.
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