For laboratory research use onlyNot for human or animal consumption

Lyophilized Peptides

GHK-CU 100MG

Gly-His-Lys-Cu(II)

A copper(II) complex of the Gly-His-Lys tripeptide used in biochemical, cell-culture and analytical research.

CatalogGHKC-PW-100MG
ManufacturerRemetide
PurityTarget ≥99% by RP-HPLC; lot result controls
Pack100 mg
$55.00 Current catalog price; lot availability controls fulfillment.
AvailabilityIn stock

12199 in stock

For laboratory research use only. Not for human or veterinary use.

01Lot documentationCOA and analytical-record model
02Defined specificationMethod and result remain lot specific
03Tracked fulfillmentShipping method and lot allocation confirmed at order review
04Responsible useNon-clinical laboratory context

Technical information

Chemical & material record

Presented in a scientific-catalog format so the material can be evaluated by identity, form and documentation before purchase.

Identity
GHK-Cu acetate
Synonyms
Gly-His-Lys-Cu(II)
CAS number
300801-03-0
Molecular formula
C14H22CuN6O4 · C2H4O2
Formula weight
462.0 Da
Sequence / identity note
Gly-His-Lys copper complex
Manufacturer
Remetide
Manufacturing role
Custom peptide synthesis and manufacture
Form
Lyophilized, non-sterile research material
Purity specification
Target ≥99% by RP-HPLC; lot result controls
Storage
-20°C, dry and protected from light; follow lot documentation
Pack size
100 mg
Catalog number
GHKC-PW-100MG

Product description

Published context, clearly separated from lot claims.

A technical catalog should make the chemical record, relevant experimental literature and product-specific documentation independently reviewable.

GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine. Published cell-culture research has examined its effects on extracellular-matrix markers, fibroblast proliferation and inflammatory signaling.

Reported studies found increased proliferation, collagen and secreted pro-MMP-2 in isolated human fibroblasts at 1 nM. In RAW 264.7 macrophage-like cells, 10 µM GHK-Cu reduced lipopolysaccharide-associated increases in reactive oxygen species, IL-6 and TNF-α. Results remain model and assay dependent.

Selected published findings

  • Examined for collagen, glycosaminoglycan, decorin and matrix-remodeling endpoints.
  • Examined for oxidative-stress and inflammatory-marker responses in cell models.
  • Used as a copper-complexed tripeptide reference in analytical and formulation research.
References and product citations 3
  1. Siméon, A., Monier, F., Emonard, H., et al. Expression and activation of matrix metalloproteinases in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. Journal of Investigative Dermatology 115(6), 962–968 (2000).
  2. Maquart, F.X., Pickart, L., Laurent, M., et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Letters 238(2), 343–346 (1988).
  3. Park, J.R., Lee, H., Kim, S.I., et al. The tripeptide GHK-Cu attenuates lipopolysaccharide-induced inflammatory processes in RAW 264.7 cells. Oncotarget 7(19), 26745–26756 (2016).

Literature interpretation: This summary describes published experimental literature and is not a lot specification, clinical claim, use instruction or representation that the supplied research material will reproduce a published result. This record intentionally excludes dosing, administration, clinical outcomes, patient eligibility and therapeutic comparisons.

Intended laboratory context

Illustrative applications

  • Analytical reference use
  • Method development
  • Comparative chromatography
  • Laboratory formulation research

Documentation package

Documentation

  • PDFCertificate of AnalysisSample
  • PDFAnalytical method noteSample
  • PDFHandling statementSample
  • PDFLot traceability recordSample
Responsible-use statement

Identity, method and release language remain subject to the approved specification and lot-specific Quality record.

Need a current record?

Documentation before decision-making.

Reference GHKC-PW-100MG and the applicable lot when contacting technical support. Published files support evaluation but do not replace the approved lot COA or material specification.

View documentation model